Figure 5

Distribution of tumor cell colony sizes. The average sizes of the tumor cell colonies as measured by digital image analysis were 16,428 pixels for the control; 9917 pixels for heparin alone; 35,760 pixels for FGF-7 alone; and 5551 pixels for the cells treated with heparin and FGF-7. Heparin significantly reduced the distribution of colony sizes in the presence or absence or FGF-7 as determined by a Mann-Whitney U-test.