Table 4 Number of risk-genotypes of three DNA repair genes and colorectal cancer risk by age at diagnosis and by tumor site

Age at diagnosis

Cases/Controls

7/20

114/126

169/155

29/17

OR

1.0

2.58

3.12

4.90

0.004

(95% CI)^a

(reference)

(1.05–6.33)

(1.28–7.58)

(1.72–14.0)

Cases/Controls

11/14

161/167

198/203

25/25

OR

1.0

1.24

1.25

1.28

0.74

(95% CI)^a

(reference)

(0.55–2.82)

(0.55–2.83)

(0.49–3.35)

Cases/Controls

10/34

132/293

177/358

23/42

OR

1.0

1.51

1.65

1.86

0.16

(95% CI)^a

(reference)

(0.72–3.14)

(0.80–3.42)

(0.78–4.44)

Cases/Controls

8/34

143/293

190/358

31/42

OR

1.0

2.13

2.32

3.18

0.03

(95% CI)^a

(reference)

(0.96–4.73)

(1.05–5.11)

(1.29–7.82)