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Table 2 Distribution of three DNA repair genes for cases and controls

From: Polymorphisms of the XRCC1, XRCC3, & XPDgenes, and colorectal cancer risk: a case-control study in Taiwan

Polymorphism

Cases, n (%)

Control, n (%)

OR (95% CI) a

XRCC1 Arg399Gln

   

   Arg/Arg

407 (56.7)

384 (52.7)

1.00

   Arg/Gln

260 (36.2)

291 (39.9)

0.84 (0.67–1.07)

   Gln/Gln

51 (7.1)

54 (7.4)

0.82 (0.53–1.25)

   Missing

9

7

 

   With Glnb

311 (43.3)

345 (47.3)

1.00

   Arg/Arg

407 (56.7)

384 (52.7)

1.18 (0.96–1.45)

XRCC3 Thr241Met

   

   Thr/Thr

660 (91.5)

658 (89.7)

1.00

   Thr/Met

60 (8.3)

74 (10.1)

0.83 (0.56–1.21)

   Met/Met

1 (0.1)

2 (0.3)

0.50 (0.05–5.51)

   Missing

6

2

 

   With Metc

61 (8.5)

76 (10.4)

1.00

   Thr/Thr

660 (91.5)

658 (89.7)

1.25 (0.88–1.79)

XPD Lys751Gln

   

   Lys/Lys

602 (84.0)

631 (86.3)

1.00

   Lys/Gln

112 (15.6)

96 (13.1)

1.29 (0.94–1.76)

   Gln/Gln

3 (0.4)

4 (0.6)

0.81 (0.18–3.62)

   Missing

10

5

 

   Lys/Lys

602 (84.0)

631 (86.3)

1.00

   With Glnd

115 (16.0)

100 (13.7)

1.20 (0.90–1.61)

  1. a: ORs and 95% CIs were estimated from unconditional logistic regressions, controlling for age and gender
  2. b: Arg/Gln+ Gln/Gln
  3. c: Thr/Met+ Met/Met
  4. d: Lys/Gln+ Gln/Gln