Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: Anthracyclines, proteasome activity and multi-drug-resistance

Figure 1

Verapamil is an inhibitor of 26S proteasome function. Incubation of crude extracts of ECV304 cells containing proteasomes with different doses of verapamil (50, 60, 80, 100, 200 μM) inhibited proteolysis of the chymotrypsin-like substrate SucLLVY-AMC in a dose-dependent manner, indicating inhibition of 26S proteasome function.

Back to article page
\