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Table 1 Clinical, pathological and genetic data of 34 ovarian cancer patients.

From: No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin

Patient

Histological type

Stage

Grade

Residual tumour

Treatment response

Exon 4 TUBB mutation

MSI status

1

Serous

III

1

> 2 cm

CR

Not present

Stable

2

Serous

III

2

< 2 cm

CR

Not present

Stable

3

Serous

III

3

> 2 cm

CR

Not present

Stable

4

Serous

III

1

> 2 cm

WR

Not present

Stable

5

Serous

III

2

> 2 cm

CR

Not present

Stable

6

Serous

III

2

< 2 cm

CR

Not present

Stable

7

Serous

III

3

> 2 cm

CR

Not present

Stable

8

Serous

III

3

> 2 cm

CR

Not present

Stable

9

Serous

III

3

> 2 cm

CR

Not present

Stable

10

Serous

III

3

> 2 cm

CR

Not present

Stable

11

Serous

III

3

> 2 cm

CR

Not present

Stable

12

Serous

III

3

> 2 cm

WR

Not present

Stable

13

Serous

III

3

> 2 cm

WR

Not present

Stable

14

Serous

IV

3

> 2 cm

PR

Not present

Stable

15

Serous

IV

3

> 2 cm

CR

Not present

Stable

16

Serous

IV

3

> 2 cm

WR

Not present

Stable

17

Serous

IV

3

> 2 cm

WR

Not present

Stable

18

Serous

IV

3

< 2 cm

CR

Not present

Stable

19

Serous

I

1

Absent

-

Not present

Stable

20

Serous

II

3

Absent

-

Not present

Stable

21

Serous

III

1

Absent

-

Not present

Stable

22

Serous

III

3

Absent

-

Not present

Stable

23

Serous

III

1

Absent

-

Not present

Stable

24

Serous

II

B

Absent

-

Not present

Stable

25

Serous

II

B

Absent

-

Not present

Stable

26

Serous

III

B

Absent

-

Not present

Stable

27

Clear cell

I

3

< 2 cm

CR

Not present

Stable

28

Clear cell

II

3

> 2 cm

WR

Not present

Stable

29

Clear cell

III

3

> 2 cm

PR

Not present

Stable

30

Clear cell

IV

3

> 2 cm

WR

Not present

Stable

31

Clear cell

I

3

Absent

-

Not present

Stable

32

Clear cell

I

3

Absent

-

Not present

Stable

33

Clear cell

II

3

Absent

-

Not present

Stable

34

Clear cell

III

3

Absent

-

Not present

Stable

  1. B: borderline tumours; CR: complete response; PR: partial response; WR: without response. The stage classification was according to the Federation Internationale de Gynecologie [21] and grading was defined as well differentiated (1), moderately differentiated (2), and poorly differentiated (3).