Skip to main content

Table 2 IC50values obtained after 24 h exposure to TPL followed by 72 h incubation in drug free medium. (mean ± s.e.m. of 4–6 independent experiments).

From: Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin

Cell lines IC25 (μM) IC50 (μM) R.I.a
HCT116 280.00 ± 39.21 560.00 ± 77.78 1.0
HT29 320.40 ± 50.03 665.63 ± 102.91 1.19
HCT116 E6 400.06 ± 60.00 837.3 ± 103.99 1.49
HCT116 p21-/- 700.00 ± 99.14 1114.55 ± 182.2 1.99
  1. a The resistance index (R.I.) was calculated as the ratio between the IC50 values obtained for each cell line and that of HCT116 cells