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Table 1 Serum antibody response after PstS1 immunotherapy

From: Immunodominant PstS1 antigen of mycobacterium tuberculosis is a potent biological response modifier for the treatment of bladder cancer

S.C. / Intravesical Treatment

Responders in %

PBS/PBS

0

L-Particle/PBS

0

L-Particle-PstS1/PBS

100

PBS/PstS1

100

L-particle/PstS1

100

L-particle-PstS1/PstS1

100

  1. Five mice per group were sensitized s.c. and treated intravesically on days 10, 17, 24 and 31 as indicated in the table. On day 32 serum of mice was obtained and analyzed for anti-PstS1 IgG by ELISA. The percentage of mice with positive anti-PstS1 antibody responses is indicated.