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Figure 4 | BMC Cancer

Figure 4

From: BAG-1 haplo-insufficiency impairs lung tumorigenesis

Figure 4

Model for cooperative action of BAG-1 and C-Raf in tumorigenesis A possible model combining the findings of this report and other data is shown. It indicates that BAG-1 functions as an activator of C-Raf at the outer mitochondrial membrane where enzymatically activated C-Raf finds apoptosis-related targets (for details see text).

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