Figure 4From: BAG-1 haplo-insufficiency impairs lung tumorigenesis Model for cooperative action of BAG-1 and C-Raf in tumorigenesis A possible model combining the findings of this report and other data is shown. It indicates that BAG-1 functions as an activator of C-Raf at the outer mitochondrial membrane where enzymatically activated C-Raf finds apoptosis-related targets (for details see text).Back to article page