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Figure 4 | BMC Cancer

Figure 4

From: Neuroblastoma and pre-B lymphoma cells share expression of key transcription factors but display tissue restricted target gene expression

Figure 4

Neuroblastoma cells express constitutive levels of Pax-5 proteins. Panel (B) shows EMSA analysis of Pax-5 (BSAP) super-shift using nuclear extracts from a set of neuroblastoma cell lines as indicated after addition of either no, anti-Pax-5 or anti actin antibody. Panel (C) shows auto radiogram with EMSAs using either a Pax-5 or an Oct binding site and nuclear extracts from SK-N-BE(2)c (neuroblastoma) cells stimulated to undergo differentiation with retinoic acid (RA) for the indicated times. The left panel displays a super-shift experiment using either actin or Pax-5 antisera.

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