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Table 1 VG-IgG2κ and VG-IgM epitope mapping

From: Fully human IgG and IgM antibodies directed against the carcinoembryonic antigen (CEA) Gold 4 epitope and designed for radioimmunotherapy (RIT) of colorectal cancers

   Tracer MAb
Gold epitope Inhibitor Mab VG-IgG2κ VG-IgM X4
1 F6 1a 2 <1
2 35A7 <1 9 3
3 B17 31 <1 13
4 CE25 99 95 83
4 X4 98 89 68
5 192 3 11 <1
  1. aResults are expressed as a percentage of inhibition of the binding of radiolabeled tracer MAbs by an excess of the reference MAbs directed against the five Gold CEA epitopes.