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Table 7 Prostate cancer: the top 10 genes and pair-wise gene expression ratio used to discriminate the prostate cancer tissues. The threshold values T i for normal tissues are also provided. The list of top 25 genes can be downloaded from http://web.hku.hk/~daniely/microarray.

From: Classification between normal and tumor tissues based on the pair-wise gene expression ratio

Prostate Cancer-Original data Prostate Cancer-Transformed data
Rank No. on array Probe no gene info Threshold Ri discriminating efficiency* / % Ref Rank gene number on array Threshold Ri discriminating efficiency* / % Ref
1 6185 37639_at Cluster Incl. X07732:Human hepatoma mRNA for serine protease hepsin <115 86.3% [18] 1 #5840/#6185 >0.37168 84.6% [18,3]
2 10537 33121_g_at Cluster Incl. AF045229:Homo sapiens regulator of G protein signaling 10 mRNA <50 80.4% [43] 2 #6185/#5840 <2.6905 84.6% [18,31]
3 8965 37720_at Cluster Incl. M22382:Human mitochondrial matrix protein P1 (nuclear encoded) mRNA <238 80.4% [44] 3 #7775/#205 <0.22928 82.7% [50,51]
4 8554 36589_at Cluster Incl. X15414:Human mRNA for aldose reductase (EC 1.1.1.2) >35 79.4% [45] 4 #8631/#10234 <5.4561 82.7% [52,53]
5 9172 38406_f_at Cluster Incl. AI207842:ao89h09.x1 Homo sapiens cDNA >626 79.4% [46] 5 #10749/#11942 <0.34585 82.7% [54]
6 7067 40436_g_at Cluster Incl. J03592:Human ADP/ATP translocase mRNA <234 78.4% [47] 6 #10234/#8631 >0.18328 82.7% [52,53]
7 9850 40282_s_at Cluster Incl. M84526:Human adipsin/complement factor D mRNA >182 77.5% [30] 7 #8554/#6185 >0.39823 82.7% [18]
8 7066 40435_at Cluster Incl. J03592:Human ADP/ATP translocase mRNA, 3 end, clone pHAT8 M96233 /FEATURE=expanded_cds/DEFINITION=HUMGSTM4A Human <349 76.5% [47] 8 #11942/#10749 >2.8914 82.7% [54,55]
9 12153 556_s_at glutathione transferase class mu number 4(GSTM4) gene >152 76.5% [48] 9 #205/#7775 >4.3614 82.7% [50,51]
10 9093 38087_s_at Cluster Incl. W72186:zd69b10.s1 Homo sapiens cDNA >62 74.5% [49] 10 #6185/#8554 <2.5111 82.7% [18]
  1. *discriminating efficiency using only single gene as discriminating axis