Table 7 Prostate cancer: the top 10 genes and pair-wise gene expression ratio used to discriminate the prostate cancer tissues. The threshold values T i for normal tissues are also provided. The list of top 25 genes can be downloaded from http://web.hku.hk/~daniely/microarray.
From: Classification between normal and tumor tissues based on the pair-wise gene expression ratio
Prostate Cancer-Original data | Prostate Cancer-Transformed data | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Rank | No. on array | Probe no | gene info | Threshold Ri | discriminating efficiency* / % | Ref | Rank | gene number on array | Threshold Ri | discriminating efficiency* / % | Ref |
1 | 6185 | 37639_at | Cluster Incl. X07732:Human hepatoma mRNA for serine protease hepsin | <115 | 86.3% | [18] | 1 | #5840/#6185 | >0.37168 | 84.6% | [18,3] |
2 | 10537 | 33121_g_at | Cluster Incl. AF045229:Homo sapiens regulator of G protein signaling 10 mRNA | <50 | 80.4% | [43] | 2 | #6185/#5840 | <2.6905 | 84.6% | [18,31] |
3 | 8965 | 37720_at | Cluster Incl. M22382:Human mitochondrial matrix protein P1 (nuclear encoded) mRNA | <238 | 80.4% | [44] | 3 | #7775/#205 | <0.22928 | 82.7% | [50,51] |
4 | 8554 | 36589_at | Cluster Incl. X15414:Human mRNA for aldose reductase (EC 1.1.1.2) | >35 | 79.4% | [45] | 4 | #8631/#10234 | <5.4561 | 82.7% | [52,53] |
5 | 9172 | 38406_f_at | Cluster Incl. AI207842:ao89h09.x1 Homo sapiens cDNA | >626 | 79.4% | [46] | 5 | #10749/#11942 | <0.34585 | 82.7% | [54] |
6 | 7067 | 40436_g_at | Cluster Incl. J03592:Human ADP/ATP translocase mRNA | <234 | 78.4% | [47] | 6 | #10234/#8631 | >0.18328 | 82.7% | [52,53] |
7 | 9850 | 40282_s_at | Cluster Incl. M84526:Human adipsin/complement factor D mRNA | >182 | 77.5% | [30] | 7 | #8554/#6185 | >0.39823 | 82.7% | [18] |
8 | 7066 | 40435_at | Cluster Incl. J03592:Human ADP/ATP translocase mRNA, 3 end, clone pHAT8 M96233 /FEATURE=expanded_cds/DEFINITION=HUMGSTM4A Human | <349 | 76.5% | [47] | 8 | #11942/#10749 | >2.8914 | 82.7% | [54,55] |
9 | 12153 | 556_s_at | glutathione transferase class mu number 4(GSTM4) gene | >152 | 76.5% | [48] | 9 | #205/#7775 | >4.3614 | 82.7% | [50,51] |
10 | 9093 | 38087_s_at | Cluster Incl. W72186:zd69b10.s1 Homo sapiens cDNA | >62 | 74.5% | [49] | 10 | #6185/#8554 | <2.5111 | 82.7% | [18] |