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Table 3 Patient tolerance

From: Chemotherapy with cisplatin and vinorelbine for elderly patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC)

  70 to 75 years > 75 years   
  80 mg/m2 90 mg/m2 60 mg/m2 70 mg/m2 Grade ≥ 3  
  3 4 3 4 3 4 3 4 n %
Haematological           
   Neutrophils 2 3 1 2 - - 1 - 9 20
   Haemoglobin 2 - 2 - - - 1 - 5 11
   Platelets - - - - - - 1 - 1 2
Clinical           
   Alopecia (grade 2) (3) (2) (1) (2) 8 18
   Fatigue 1 - 2 - - - 1 - 4 9
   Nausea and vomiting - - - - - - - - -  
   Neurosensory 1 - - - - - - - 1 2
   Renal - - - - - - - - -  
   Infection - - 1 - - - - - 1 2
Early death - 2 - - 2 4
Toxic death - 1 - - 1 2