Skip to main content

Advertisement

Table 2 Therapy results

From: Chemotherapy with cisplatin and vinorelbine for elderly patients with locally advanced or metastatic non-small-cell lung cancer (NSCLC)

  Study Group Total
  70 to 75 years > 75 years  
  80 mg/m2 (n = 15) 90 mg/m2 (n = 14) 60 mg/m2 (n = 7) 70 mg/m2 (n = 8) (n = 44)
Treatment administered      
   Chemotherapy cycles      
No. 46 42 14 23 125
Median (range) 2 (1 to 4) 2 (1 to 5) 3 (1 to 5) 3 (1 to 6) 3 (1 to 6)
   Vinorelbine (median, mg/m2/wk) 8.6 8.8 9.4 10.3 8.9
   Cisplatin (median, mg/m2/wk) 13.6 15.9 11.2 14.4 14.5
Efficacy      
   Complete response - - - 1 1
   Partial response 8 8 2 3 21
   Stable disease 4 4 3 2 13
   Progressive disease 2 1 - - 3
   Not evaluated 1 1 2 2 6
   Overall response rate (%) 53 57 29 50 50
Time to progression (median, in weeks) 25.0 23.0 15.7 18.4 27.0
Overall Survival      
   Median (weeks) 31.0 17.3 26.6 31.7 30.1
   1-year (%) 40.0 35.7 28.5 37.5 36.3