Figure 4

Hierarchical clustering of genes regulated after tipifarnib treatment. A fold-change ratio was calculated using the treated sample and its matched untreated sample. Duplicate samples are indicated with suffices "a" and "b". Number suffices indicate day of treatment. The color bar indicates the fold-change (log₂). Red is up-regulated, blue is down-regulated. White indicates no change. Cluster A and B were associated with genes that were largely down- and up-regulated across all samples, respectively.