No evidence for involvement of SDHD in neuroblastoma pathogenesis

BMC Cancer

Table 5 Ultrastructural analysis of mitochondria

	dilation of cristae*	density of matrix°	configuration#	matrix granules°°	mean projected length (μm)	max projected length (μm)
CHP-901	+	-+	+	+	0,65	1,31
CLB-GA	++	+		+	0,69	1,92
IMR-32	+	+	+	-	0,69	1,27
LA-N-2	++	+		-	0,82	2,18
MCF-7	-	+	+	-	1,06	3,11
N-206	+++	+		-	0,84	1,65
NGP	+++	+		-	0,84	1,74
NMB	-	-	+	-	0,68	1,26
SJNB-10	+++	+		-	0,63	1,69
SJNB-12	+	+		-	0,47	1,23
SJNB-8	-	-+	+	-	1,02	3,40
SK-N-AS	++	+		-	0,66	1,47
SK-N-FI	+	-	+	-	0,65	1,32
SK-N-MC	-	-	+	-	0,90	2,03
SK-N-SH	+	-+	+	+	0,56	1,31

*: +cristae of some mitochondria dilated; ++cristae of many mitochondria dilated; +++all mitochondria have dilated cristae;
°: +matrix of most mitochondria is more electron dense than the cytosol; -+part of the mitochondria are dense, but others have a light matrix; -mitochondrial matrix is lighter than or equal to cytosol;
#: +mitochondria with an orthodox configuration are present; in the same cell or culture other mitochondria may have dilated cristae and a dense matrix;
°°: -few or no matrix granules; +matrix granules visible in many or most mitochondria, normal image;

ISSN: 1471-2407