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Table 5 Ultrastructural analysis of mitochondria

From: No evidence for involvement of SDHD in neuroblastoma pathogenesis

  dilation of cristae* density of matrix° configuration# matrix granules°° mean projected length (μm) max projected length (μm)
CHP-901 + -+ + + 0,65 1,31
CLB-GA ++ +   + 0,69 1,92
IMR-32 + + + - 0,69 1,27
LA-N-2 ++ +   - 0,82 2,18
MCF-7 - + + - 1,06 3,11
N-206 +++ +   - 0,84 1,65
NGP +++ +   - 0,84 1,74
NMB - - + - 0,68 1,26
SJNB-10 +++ +   - 0,63 1,69
SJNB-12 + +   - 0,47 1,23
SJNB-8 - -+ + - 1,02 3,40
SK-N-AS ++ +   - 0,66 1,47
SK-N-FI + - + - 0,65 1,32
SK-N-MC - - + - 0,90 2,03
SK-N-SH + -+ + + 0,56 1,31
  1. *: +cristae of some mitochondria dilated; ++cristae of many mitochondria dilated; +++all mitochondria have dilated cristae;
  2. °: +matrix of most mitochondria is more electron dense than the cytosol; -+part of the mitochondria are dense, but others have a light matrix; -mitochondrial matrix is lighter than or equal to cytosol;
  3. #: +mitochondria with an orthodox configuration are present; in the same cell or culture other mitochondria may have dilated cristae and a dense matrix;
  4. °°: -few or no matrix granules; +matrix granules visible in many or most mitochondria, normal image;