Table 1 Correlation of chromosomal changes with clinical and histologic paramaters, and HPV status in CC patients

Histology

   SCC (N = 72)

14

42

41

4.71 ± 3.64

3.93 ± 3.22

8.64 ± 6.31

   AC (N = 5)

1

2

1

5.80 ± 3.63

3.20 ± 3.77

9.00 ± 7.11

Significance

p = 1.00

p = 0.65

p = 0.17

p = 0.52

p = 0.63

p = 0.90

Stage

   I (N = 14)

1

8

6

5.00 ± 3.57

3.71 ± 2.95

8.71 ± 6.08

   II (N = 18)

4

12

13

5.11 ± 3.80

3.94 ± 2.84

9.06 ± 6.16

   III-IV (N = 45)

10

24

20

4.58 ± 3.65

3.91 ± 3.52

8.49 ± 6.57

Significance

p = 0.45

p = 0.63

p = 0.20

p = 0.85

p = 0.98

p = 0.95

Size of tumor

   1–5 cm (N = 29)

6

20

15

5.62 ± 4.02

4.10 ± 3.26

9.72 ± 6.84

   ≥6 cm (N = 38)

6

18

20

4.18 ± 3.52

4.05 ± 3.48

8.24 ± 6.40

Significance

p = 0.60

p = 0.08

p = 0.94

p = 0.12

p = 0.95

p = 0.36

Age (yrs)

   ≤40 (N = 31)

8

21

16

4.58 ± 3.67

3.58 ± 2.67

8.16 ± 5.78

   41–60 (N = 28)

5

12

13

5.39 ± 3.73

4.32 ± 3.37

9.71 ± 6.55

   ≥60 (N = 18)

2

11

13

4.17 ± 3.47

3.72 ± 3.95

7.89 ± 6.93

Significance

p = 0.44

p = 0.14

p = 0.13

p = 0.50

p = 0.67

p = 0.54

HPV type

   HPV16 (N = 45)

7

27

26

4.62 ± 3.49

3.33 ± 2.85

7.96 ± 5.68

   HPV18 (N = 4)

3

3

3

10.00 ± 5.48

8.75 ± 6.06

18.75 ± 11.53

   Multiple (N = 10)

3

4

2

4.40 ± 2.37

4.10 ± 2.96

8.50 ± 4.74

   Others (N = 16)

2

9

10

3.94 ± 3.00

3.81 ± 2.71

7.75 ± 5.11

   Significance

p = 0.04

p = 0.11

p = 0.02

p = 0.01

p = 0.01

Treatment response

CR (N= 34)

5

21

21

4.91 ± 3.78

3.79 ± 3.46

8.71 ± 6.67

DOD/PR (N = 43)

10

23

21

4.67 ± 3.54

3.95 ± 3.08

8.63 ± 6.09

Significance

p = 0.35

p = 0.26

p = 0.78

p = 0.83

p = 0.96