Figure 4
Inhibition of (A) tamoxifen (16 μM)-stimulated basal and (B) tamoxifen-stimulated induced 6-keto-PGF1α production (lactacystin in the presence of TPA) by celecoxib (*) and piroxicam (◊). Rat liver cells were incubated with either (A) tamoxifen (16 μM) or (B) lactacystin plus TPA in the presence of tamoxifen, for 6-h. The analyses were performed with triplicate dishes.