Figure 3
Effect of tamoxifen, LY117018 or raloxifene on (A) basal 6-keto-PGF1α production and (B) the effect of tamoxifen or LY117018 on 6-keto-PGF1α production induced by lactacystin in the presence of TPA. Rat liver cells were incubated for 6-h. The analyses were performed with triplicate or quadruplicate dishes. Each bar gives the mean value and the brackets the SEM. * = Statistically significant vs control stimulation. ** = Statistically significant vs lactacystin plus TPA control. The data are representative of several independent experiments with the same results.