Ancestry reported by white adults with cutaneous melanoma and control subjects in central Alabama

BMC Cancer

Table 1 Frequencies of Country of Ancestry Reports in Adult Whites in Central Alabama. *

Country	Melanoma Probands % (n)	Control Subjects % (n)	P Value^†
England	46.7 (42)	43.9 (140)	0.6394
Ireland	62.2 (56)	45.1 (144)	0.0042
Scotland	44.4 (40)	27.0 (86)	0.0015
Ireland + Scotland ("Celts")	67.8 (61)	55.8 (178)	0.0417
Wales	0 (0)	4.7 (15)	0.0223
British Isles	73.3 (66)	75.6 (241)	0.6679
Native American	16.7 (15)	23.8 (76)	0.1493
Germany	24.4 (22)	33.5 (107)	0.1009
France	5.6 (5)	14.1 (45)	0.0287
Norway	1.1 (1)	1.6 (5)	0.6059
Netherlands	6.7 (6)	9.1 (29)	0.4678
Lithuania	0 (0)	0.3 (1)	0.7800
Czechoslovakia	1.1 (1)	0.9 (3)	0.6315
Spain	0 (0)	2.2 (7)	0.1730
Austria	1.1 (1)	2.2 (7)	0.4442
Belgium	1.1 (1)	0.3 (1)	0.3921
Denmark	1.1 (1)	1.6 (5)	0.6059
Finland	0 (0)	0.3 (1)	0.7800
Greece	2.2 (2)	1.3 (4)	0.3941
Hungary	1.1 (1)	0.6 (2)	0.5265
Italy	0 (0)	5.6 (18)	0.0102
Poland	0 (0)	5.0 (16)	0.0172
Romania	0 (0)	0.6 (2)	0.6079
Russia	0 (0)	2.5 (8)	0.1343
Sicily	0 (0)	1.6 (5)	0.2866
Sweden	1.1 (1)	4.4 (14)	0.1211
Switzerland	0 (0)	1.3 (4)	0.3685
Europe Not British Isles	63.3 (57)	62.7 (200)	0.9120
North, Central, and South American Countries	4.4 (4)	2.2 (7)	0.2057
Near and Middle East Countries	1.1 (1)	0.9 (3)	0.6315
African Countries	0 (0)	0.3 (1)	0.7800
Don't Know	30.0 (27)	30.1 (96)	0.9863

*These data include all reports by each evaluable study participant; there were 90 evaluable melanoma probands and 319 evaluable control subjects. The category "British Isles" was defined as the reports in England, Ireland, Scotland, and Wales categories. The category "Europe Not British Isles" is comprised of the composite data from the corresponding individual countries displayed in the present table. Participants who indicated specific "Native American" ancestry most frequently reported Cherokee and Creek descent. The "North, Central, and South America Countries" category (other than "Native Americans") included Canada, U.S., Virgin Islands, Colombia, and Brazil. The category "Near and Middle East Countries" included reports about grandparents from Iran, Lebanon, and Syria. The single observation in "African Countries" represents the Republic of South Africa. The "Don't Know" categories include data from participants who reported this category for one, two, or three grandparents. ^†Chi-square or Fisher exact tests were used, as appropriate; p values < 0.05 were defined as significant.

ISSN: 1471-2407