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Table 2 Fold change in HIP for human tumor vs. normal tissues.

From: Hedgehog-interacting protein is highly expressed in endothelial cells but down-regulated during angiogenesis and in several human tumors

Tissue

Sex

Race

Age

Tumor additional information

HIP tumor/normal*

Liver

M

C

59

Primary cancer of the liver

0.41

 

M

C

36

Primary cancer of the liver

0.06

 

M

C

58

Primary cancer of the liver

0.03

     

HIP decreases in 3/3

Stomach

M

C

63

Adenocarcinoma

0.16

 

M

C

57

Gastric cancer

1.61

 

M

C

47

Gastric cancer

0.24

 

M

C

65

Adenocarcinoma

0.21

 

M

C

61

Adenocarcinoma

0.24

 

M

C

50

Mucinous adenocarcinoma

0.53

 

F

C

72

Adenocarcinoma

0.68

 

F

C

67

Adenocarcinoma

0.37

 

M

C

75

Adenocarcinoma

0.03

 

F

C

68

Adenocarcinoma

0.21

     

HIP decreases in 9/10

Colon

F

C

67

Adenocarcinoma

0.25

 

F

C

58

Tubulovillous adenoma

0.23

 

F

C

43

Adenocarcinoma

0.85

 

F

C

69

Adenocarcinoma

1.34

 

F

C

35

Adenocarcinoma

0.41

 

M

C

58

Adenocarcinoma

0.4

 

M

C

63

Adenocarcinoma

0.24

 

F

C

73

Adenocarcinoma

0.16

 

F

C

65

Adenocarcinoma

1.68

 

F

C

65

Adenocarcinoma

0.14

     

HIP decreases in 8/10

Rectum

F

A

44

Mucinous adenocarcinoma

0.25

 

M

C

68

Adenocarcinoma

1.1

 

F

C

49

Adenocarcinoma

0.18

 

F

C

59

Adenocarcinoma

0.22

 

F

C

53

Mucinous adenocarcinoma

0.08

 

F

C

70

Adenocarcinoma

1.05

 

M

C

42

Adenocarcinoma

0.79

 

F

C

71

Adenocarcinoma

0.59

 

F

C

59

Adenocarcinoma

0.15

 

M

C

43

Adenocarcinoma

0.56

     

HIP decreases in 8/10

Lung

F

C

69

Bronchiolo-alveolar adenocarcinoma

6.45

 

M

C

72

Central cancer of the right lung

0.36

 

M

C

66

Central cancer of the middle lobe of rt lung

0.23

 

M

C

51

Peripheral cancer of the upper lobe of rt lung

0.45

 

M

C

63

Squamous cell carcinoma, keratinizing type

5.49

 

M

C

62

Squamous cell carcinoma, keratinizing type

0.19

 

M

C

67

Squamous cell carcinoma

0.4

 

M

C

71

Squamous cell carcinoma, keratinizing type

0.95

 

M

C

65

Adenocarcinoma

4.9

 

M

A

52

Squamous cell carcinoma

7.08

     

HIP decreases in 5/10

  1. *HIP tumor/normal value is the vWF-normalized quantity of HIP for the tumor, divided by the vWF-normalized quantity of HIP for the corresponding normal tissue.
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BMC Cancer

ISSN: 1471-2407

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