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Table 8 MT1-MMP and MMP-11 Target:Control ratios for 24 and 48 hour treatments normalised to 18S rRNA of NIH3T3 cells of MEF cells.

From: Stimulation of MMP-11 (stromelysin-3) expression in mouse fibroblasts by cytokines, collagen and co-culture with human breast cancer cell lines

Treatment

Target:Control Ratio

 

24 Hour

48 Hour

 

MT1-MMP ± SEM

MMP-11 ± SEM

MT1-MMP ± SEM

MMP-11 ± SEM

Control

1.00 ± 0.02

1.00 ± 0.02

1.00 ± 0.08

1.00 ± 0.04

Collagen I

1.28 ± 0.04

1.30 ± 0.6

1.28 ± 0.08

1.32 ± 0.04

Collagen IV

1.35 ± 0.05

0.76 ± 0.04

1.35 ± 0.05

0.68 ± 0.02

Collagen V

1.54 ± 0.02

1.45 ± 0.10

2.85 ± 0.35

1.68 ± 0.04

Con-A

1.00 ± 0.02

1.26 ± 0.06

1.00 ± 0.02

1.35 ± 0.05

TGF-β

0.75 ± 0.05

0.65 ± 0.03

2.60 ± 0.18

1.44 ± 0.12

Fibronectin

0.85 ± 0.05

0.90 ± 0.04

4.20 ± 0.26

1.86 ± 0.18

IL-1β

0.68 ± 0.08

0.70 ± 0.04

4.00 ± 0.20

1.95 ± 0.17

IL-2

0.74 ± 0.06

0.68 ± 0.02

3.14 ± 0.26

1.44 ± 0.10

IL-6

0.70 ± 0.02

0.80 ± 0.05

1.74 ± 0.12

1.15 ± 0.07