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Table 7 MT1-MMP and MMP-11 Target:Control ratios for 24 and 48 hour treatments normalised to 18S rRNA of NIH3T3 cells.

From: Stimulation of MMP-11 (stromelysin-3) expression in mouse fibroblasts by cytokines, collagen and co-culture with human breast cancer cell lines

Treatment Target:Control Ratio
  24 Hour 48 Hour
  MT1-MMP ± SEM MMP-11 ± SEM MT1-MMP ± SEM MMP-11 ± SEM
Control 1.00 ± 0.02 1.00 ± 0.02 1.00 ± 0.08 1.00 ± 0.04
Collagen I 1.32 ± 0.08 1.35 ± 0.10 1.32 ± 0.08 1.27 ± 0.08
Collagen IV 1.26 ± 0.06 0.68 ± 0.08 1.26 ± 0.06 0.71 ± 0.10
Collagen V 1.60 ± 0.08 1.65 ± 0.08 3.55 ± 0.35 1.91 ± 0.08
Con-A 1.00 ± 0.02 1.35 ± 0.12 1.00 ± 0.02 1.41 ± 0.14
TGF-β 0.62 ± 0.04 0.56 ± 0.06 2.95 ± 0.25 1.67 ± 0.14
Fibronectin 0.75 ± 0.08 0.72 ± 0.08 4.65 ± 0.38 2.16 ± 0.24
IL-1β 0.72 ± 0.10 0.78 ± 0.04 4.32 ± 0.28 2.20 ± 0.24
IL-2 0.68 ± 0.08 0.70 ± 0.08 3.36 ± 0.30 1.57 ± 0.16
IL-6 0.70 ± 0.04 0.74 ± 0.04 1.90 ± 0.14 1.27 ± 0.08