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Table 7 MT1-MMP and MMP-11 Target:Control ratios for 24 and 48 hour treatments normalised to 18S rRNA of NIH3T3 cells.

From: Stimulation of MMP-11 (stromelysin-3) expression in mouse fibroblasts by cytokines, collagen and co-culture with human breast cancer cell lines

Treatment

Target:Control Ratio

 

24 Hour

48 Hour

 

MT1-MMP ± SEM

MMP-11 ± SEM

MT1-MMP ± SEM

MMP-11 ± SEM

Control

1.00 ± 0.02

1.00 ± 0.02

1.00 ± 0.08

1.00 ± 0.04

Collagen I

1.32 ± 0.08

1.35 ± 0.10

1.32 ± 0.08

1.27 ± 0.08

Collagen IV

1.26 ± 0.06

0.68 ± 0.08

1.26 ± 0.06

0.71 ± 0.10

Collagen V

1.60 ± 0.08

1.65 ± 0.08

3.55 ± 0.35

1.91 ± 0.08

Con-A

1.00 ± 0.02

1.35 ± 0.12

1.00 ± 0.02

1.41 ± 0.14

TGF-β

0.62 ± 0.04

0.56 ± 0.06

2.95 ± 0.25

1.67 ± 0.14

Fibronectin

0.75 ± 0.08

0.72 ± 0.08

4.65 ± 0.38

2.16 ± 0.24

IL-1β

0.72 ± 0.10

0.78 ± 0.04

4.32 ± 0.28

2.20 ± 0.24

IL-2

0.68 ± 0.08

0.70 ± 0.08

3.36 ± 0.30

1.57 ± 0.16

IL-6

0.70 ± 0.04

0.74 ± 0.04

1.90 ± 0.14

1.27 ± 0.08