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Table 2 Genes with high expression in HCT-116 tumors grown in Nu/Nu mice

From: The influence of tumor size and environment on gene expression in commonly used human tumor lines

Function Affymetrix Probe Set ID ANOVA p-value BH p-value1 Log2 FC2 Gene Symbol LocusLink ID Sequence Probe Derived From Gene Title
Translation/RNA binding/RNA splicing
  32276_at 0.00036 0.047 -0.5 RPL32 6161 X03342 ribosomal protein L32
  32432_f_at 0.00032 0.046 -0.6 RPL15 6138 L25899 ribosomal protein L15
  33614_at 0.00028 0.046 -0.5 RPL18A 6142 X80822 ribosomal protein L18a
  33660_at 0.00039 0.048 -0.5 RPL5 6125 U14966 ribosomal protein L5
  34317_g_at 0.00029 0.046 -0.5 RPS15A 6210 W52024 ribosomal protein S15a
  34345_at 0.00043 0.049 -0.1 C20orf14 24148 AF026031 chromosome 20 open reading frame 14
  398_at 0.00029 0.046 -0.6 DDX18 8886 X98743 DEAD/H box polypeptide 18 (Myc-regulated)
  40887_g_at 0.00017 0.046 -0.5 EEF1A1 1915 L41498 eukaryotic translation elongation factor 1 alpha 1
Signal Transduction
  35772_at 0.00029 0.046 -0.9 ARHGEF12 23365 AB002380 Rho guanine nucleotide exchange factor (GEF) 12
  36091_at 0.00038 0.048 -0.6 SCAP2 8935 AF051323 src family associated phosphoprotein 2
  40784_at 0.00003 0.028 -0.7 PPP2R5C 5527 Z69030 protein phosphatase 2, regulatory subunit B (B56), gamma isoform
  769_s_at 0.00032 0.046 -0.3 ANXA2 302 D00017 annexin A2
  777_at 0.00010 0.039 -0.6 GDI2 2665 D13988 GDP dissociation inhibitor 2
Unknown or Other Functions
  1160_at 0.00024 0.046 -0.3 CYC1 1537 J04444 cytochrome c-1
  1226_at 0.00010 0.039 -0.5 ADAM17 6868 U69611 a disintegrin and metalloproteinase domain 17
  31531_g_at 0.00007 0.030 -0.5 ACACB 32 U89344 acetyl-Coenzyme A carboxylase beta
  31684_at 0.00004 0.030 -0.8 ANXA2P1 303 M62896 annexin A2 pseudogene 1
  32518_at 0.00014 0.042 -0.6 ZNF259 8882 AF019767 zinc finger protein 259
  33363_at 0.00041 0.049 -0.1 JTV1 7965 W25934 JTV1 gene
  33389_at 0.00017 0.046 -1.0 CYP51 1595 U23942 cytochrome P450, 51
  33558_at 0.00012 0.039 -0.5 TBX5 6910 Y09445 T-box 5
  33820_g_at 0.00000 0.007 -0.7 HSPA8 3312 X13794 heat shock 70 kDa protein 8
  33937_at 0.00021 0.046 -0.6    AJ011981 Homo sapiens mRNA sequence, IMAGE clone 417820
  34808_at 0.00022 0.046 -0.4    AB023216 KIAA0999 protein
  37218_at 0.00029 0.046 -0.4 BTG3 10950 D64110 BTG family, member 3
  38553_r_at 0.00025 0.046 -1.3 BAP29 55973 AI984786 B-cell receptor-associated protein BAP29
  38589_i_at 0.00042 0.049 -0.6 PTMA 5757 M14630 prothymosin, alpha (gene sequence 28)
  39167_r_at 0.00045 0.050 -1.2 SERPINH2 872 D83174 serine (or cysteine) proteinase inhibitor, clade H, member 2
  418_at 0.00004 0.030 -0.5 MKI67 4288 X65550 antigen identified by monoclonal antibody Ki-67
  893_at 0.00003 0.028 -0.4 E2-EPF 27338 M91670 ubiquitin carrier protein
  932_i_at 0.00031 0.046 -0.8 ZNF91 7644 L11672 zinc finger protein 91
  1. 1p-value resulting from Benjamini and Hochberg procedure 2 log2 fold change calculated by dividing expression level from C.B-17 SCID sample by expression level of Nu/Nu sample
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BMC Cancer

ISSN: 1471-2407

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