Table 2 Genes with high expression in HCT-116 tumors grown in Nu/Nu mice
From: The influence of tumor size and environment on gene expression in commonly used human tumor lines
Function | Affymetrix Probe Set ID | ANOVA p-value | BH p-value1 | Log2 FC2 | Gene Symbol | LocusLink ID | Sequence Probe Derived From | Gene Title |
|---|---|---|---|---|---|---|---|---|
Translation/RNA binding/RNA splicing | ||||||||
| Â | 32276_at | 0.00036 | 0.047 | -0.5 | RPL32 | 6161 | X03342 | ribosomal protein L32 |
| Â | 32432_f_at | 0.00032 | 0.046 | -0.6 | RPL15 | 6138 | L25899 | ribosomal protein L15 |
| Â | 33614_at | 0.00028 | 0.046 | -0.5 | RPL18A | 6142 | X80822 | ribosomal protein L18a |
| Â | 33660_at | 0.00039 | 0.048 | -0.5 | RPL5 | 6125 | U14966 | ribosomal protein L5 |
| Â | 34317_g_at | 0.00029 | 0.046 | -0.5 | RPS15A | 6210 | W52024 | ribosomal protein S15a |
| Â | 34345_at | 0.00043 | 0.049 | -0.1 | C20orf14 | 24148 | AF026031 | chromosome 20 open reading frame 14 |
| Â | 398_at | 0.00029 | 0.046 | -0.6 | DDX18 | 8886 | X98743 | DEAD/H box polypeptide 18 (Myc-regulated) |
| Â | 40887_g_at | 0.00017 | 0.046 | -0.5 | EEF1A1 | 1915 | L41498 | eukaryotic translation elongation factor 1 alpha 1 |
Signal Transduction | ||||||||
| Â | 35772_at | 0.00029 | 0.046 | -0.9 | ARHGEF12 | 23365 | AB002380 | Rho guanine nucleotide exchange factor (GEF) 12 |
| Â | 36091_at | 0.00038 | 0.048 | -0.6 | SCAP2 | 8935 | AF051323 | src family associated phosphoprotein 2 |
| Â | 40784_at | 0.00003 | 0.028 | -0.7 | PPP2R5C | 5527 | Z69030 | protein phosphatase 2, regulatory subunit B (B56), gamma isoform |
| Â | 769_s_at | 0.00032 | 0.046 | -0.3 | ANXA2 | 302 | D00017 | annexin A2 |
| Â | 777_at | 0.00010 | 0.039 | -0.6 | GDI2 | 2665 | D13988 | GDP dissociation inhibitor 2 |
Unknown or Other Functions | ||||||||
| Â | 1160_at | 0.00024 | 0.046 | -0.3 | CYC1 | 1537 | J04444 | cytochrome c-1 |
| Â | 1226_at | 0.00010 | 0.039 | -0.5 | ADAM17 | 6868 | U69611 | a disintegrin and metalloproteinase domain 17 |
| Â | 31531_g_at | 0.00007 | 0.030 | -0.5 | ACACB | 32 | U89344 | acetyl-Coenzyme A carboxylase beta |
| Â | 31684_at | 0.00004 | 0.030 | -0.8 | ANXA2P1 | 303 | M62896 | annexin A2 pseudogene 1 |
| Â | 32518_at | 0.00014 | 0.042 | -0.6 | ZNF259 | 8882 | AF019767 | zinc finger protein 259 |
| Â | 33363_at | 0.00041 | 0.049 | -0.1 | JTV1 | 7965 | W25934 | JTV1 gene |
| Â | 33389_at | 0.00017 | 0.046 | -1.0 | CYP51 | 1595 | U23942 | cytochrome P450, 51 |
| Â | 33558_at | 0.00012 | 0.039 | -0.5 | TBX5 | 6910 | Y09445 | T-box 5 |
| Â | 33820_g_at | 0.00000 | 0.007 | -0.7 | HSPA8 | 3312 | X13794 | heat shock 70 kDa protein 8 |
| Â | 33937_at | 0.00021 | 0.046 | -0.6 | Â | Â | AJ011981 | Homo sapiens mRNA sequence, IMAGE clone 417820 |
| Â | 34808_at | 0.00022 | 0.046 | -0.4 | Â | Â | AB023216 | KIAA0999 protein |
| Â | 37218_at | 0.00029 | 0.046 | -0.4 | BTG3 | 10950 | D64110 | BTG family, member 3 |
| Â | 38553_r_at | 0.00025 | 0.046 | -1.3 | BAP29 | 55973 | AI984786 | B-cell receptor-associated protein BAP29 |
| Â | 38589_i_at | 0.00042 | 0.049 | -0.6 | PTMA | 5757 | M14630 | prothymosin, alpha (gene sequence 28) |
| Â | 39167_r_at | 0.00045 | 0.050 | -1.2 | SERPINH2 | 872 | D83174 | serine (or cysteine) proteinase inhibitor, clade H, member 2 |
| Â | 418_at | 0.00004 | 0.030 | -0.5 | MKI67 | 4288 | X65550 | antigen identified by monoclonal antibody Ki-67 |
| Â | 893_at | 0.00003 | 0.028 | -0.4 | E2-EPF | 27338 | M91670 | ubiquitin carrier protein |
| Â | 932_i_at | 0.00031 | 0.046 | -0.8 | ZNF91 | 7644 | L11672 | zinc finger protein 91 |