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Table 1 Genes with high expression in HCT-116 tumors grown in C.B-17 SCID mice

From: The influence of tumor size and environment on gene expression in commonly used human tumor lines

Function Affymetrix Probe Set ID ANOVA p-value BH p-value1 Log2 FC2 Gene Symbol LocusLink ID Sequence Probe Derived From Gene Title
Translation/RNA binding/RNA splicing
  34733_at 0.00029 0.046 0.5 SF3A1 10291 X85237 splicing factor 3a, subunit 1, 120 kDa
  34829_at 0.00020 0.046 0.4 DKC1 1736 U59151 dyskeratosis congenita 1, dyskerin
  35174_i_at 0.00020 0.046 0.4 EEF1A2 1917 X70940 eukaryotic translation elongation factor 1 alpha 2
  37462_i_at 0.00013 0.042 0.5 SF3A2 8175 L21990 splicing factor 3a, subunit 2, 66 kDa
  39047_at 0.00007 0.030 0.5 SART3 9733 AB020880 squamous cell carcinoma antigen recognised by T cells 3
  40490_at 0.00041 0.049 0.7 DDX21 9188 U41387 DEAD/H box polypeptide 21
Signal transduction
  33887_at 0.00029 0.046 0.5 HGS 9146 D84064 hepatocyte growth factor-regulated tyrosine kinase substrate
  38019_at 0.00002 0.028 1.0 CSNK1E 1454 L37043 casein kinase 1, epsilon
  38779_r_at 0.00039 0.048 0.8 HDGF 3068 D16431 hepatoma-derived growth factor
  40864_at 0.00029 0.046 0.4 RAC1 5879 D25274 ras-related C3 botulinum toxin substrate
Small Molecule transport
  32186_at 0.00023 0.046 0.7 SLC7A5 8140 M80244 solute carrier family 7, member 5
  36557_at 0.00003 0.028 0.9 CACNB1 782 M92303 calcium channel, voltage-dependent, beta 1 subunit
  38029_at 0.00031 0.046 0.4 SLC3A2 6520 J02939 solute carrier family, member 2
Protein Complex Assembly
  31842_at 0.00044 0.050 0.5 BCS1L 617 AF038195 BCS1-like (yeast)
  32575_at 0.00019 0.046 0.4 NAP1L4 4676 U77456 nucleosome assembly protein 1-like 4
Protein transport and folding
  36945_at 0.00036 0.047 0.5 C12orf8 10961 X94910 chromosome 12 open reading frame 8
  40756_at 0.00017 0.046 0.4 NPM3 10360 AF081280 nucleophosmin/nucleoplasmin, 3
Unknown or other functions
  31670_s_at 0.00023 0.046 0.3 SRP72 6731 U81554 signal recognition particle 72 kDa
  34279_at 0.00005 0.030 2.0 FLJ20719 55672 AL050141 hypothetical protein FLJ20719
  36192_at 0.00003 0.028 0.7 KIAA0193 9805 D83777 KIAA0193 gene product
  36209_at 0.00003 0.028 0.8 BRD2 6046 S78771 bromodomain containing 2
  36210_g_at 0.00035 0.047 1.0 BRD2 6046 S78771 bromodomain containing 2
  36668_at 0.00035 0.047 0.4 DIA1 1727 M28713 diaphorase (NADH)
  37907_at 0.00006 0.030 0.4 F8A 8263 M34677 coagulation factor VIII-associated
  38885_at 0.00000 0.007 1.0 DNA2L 1763 D42046 DNA2 DNA replication helicase 2-like
  39436_at 0.00010 0.039 1.5 BNIP3L 665 AF079221 BCL2/adenovirus E1B 19 kDa interacting protein 3-like
  39758_f_at 0.00030 0.046 0.4 LAMP1 3916 J04182 lysosomal-associated membrane protein 1
  39832_at 0.00007 0.030 0.5 ARS2 51593 AL096723 arsenate resistance protein ARS2
  40589_at 0.00041 0.049 0.9 SNTB2 6645 U40572 syntrophin, beta 2
  40604_at 0.00012 0.040 1.1 DYRK2 8445 Y13493 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
  41062_at 0.00028 0.046 0.7 NSPC1 84759 AA037278 likely ortholog of mouse nervous system polycomb 1
  982_at 0.00011 0.039 0.4 MCM5 4174 X74795 MCM5 minichromosome maintenance deficient 5, cell division cycle 46
  1. 1p-value resulting from Benjamini and Hochberg procedure 2 log2 fold change calculated by dividing expression level from C.B-17 SCID sample by expression level of Nu/Nu sample