Figure 1
From: Is the gene encoding Chibby implicated as a tumour suppressor in colorectal cancer ?
Microsatellite markers used for genotyping of chromosome 22. Genotyper® graphs obtained after multiplex PCR of the five microsatellite markers on chromosome 22 are shown on A, B, C, D, E. In each case the upper graph corresponds to the tumour DNA and the lower graph to the matched normal colonic mucosa DNA. Peaks are labelled with: name of markers, size of PCR products (bp) and peak intensity. A and B show no allelic loss for D22S420 and D22S315, whereas C, D and E show allelic loss for DS22S283, D22S423, D22S274. These results suggest a distal deletion of chromosome 22 including the C22orf2 gene.