Skip to main content

Table 1 Novel and high frequency mtDNA polymorphisms detected in Shanxi, China.

From: Control region mutations and the 'common deletion' are frequent in the mitochondrial DNA of patients with esophageal squamous cell carcinoma

Nucleotide Position Base Change Healthy Reference Samples (n = 23) ESCC Case Samples (n = 21)
73 A-G 21 21
150 C-T 10 4
152 T-C 6 5
179 T-C* 1 0
195 T-C 5 2
249 A del 4 5
263 A-G 21 21
309 C-CC/CCC 16/6 12/4
310–311 TC del* 1 0
315 C-CC 19 21
320 C-T* 2 0
358 A-C* 2 0
368 A-G* 0 1
489 T-C 12 14
523–524 AC del* 6 7
548 C-T* 0 1
574 A-G* 0 1
16155 A-T* 1 0
16163 A-C* 1 0
16172 T-C 2 6
16183 A-C 6 5
16223 C-T 19 13
16289 A-C* 0 1
16298 T-C 4 5
16362 T-C 9 7
16519 T-C 12 9
16524 A-T* 0 1
  1. Novel polymorphisms (denoted by *) were those not reported in the Mitomap database as of 6/01/2003. High frequency was defined as polymorphisms present in ≥ 5 samples in either group. Nucleotide position was defined by the Cambridge reference sequence (GenBank NC 001807).
\