Figure 1From: Microarray analysis in clinical oncology: pre-clinical optimization using needle core biopsies from xenograft tumors Correlations using amplified and total RNA isolated from U251 tumor. (A) Correlations between gene expression ratios for all genes using amplified RNA replicates 0.951 (n = 6,841 genes) and (B) total RNA replicates 0.919 (n = 6,981 genes). (D) and (E) represent scatter plots and correlations obtained for amplified 0.995 (n = 456 genes) and total replicates 0.995 (n = 274 genes), respectively, for outlier gene expression. (C) and (F) Representative correlation between total and amplified RNA from one sample 0.73 for all genes (n = 6,987 genes) and 0.945 for outliers (n = 203 genes). Extraction methods for all genes and outliers are found in the methods.Back to article page