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Table 3 RT-PCR. Level of expression of Core I in tumours and corresponding normal tissues.

From: Core I gene is overexpressed in Hürthle and non-Hürthle cell microfollicular adenomas and follicular carcinomas of the thyroid

Case Age/Sex Diagnosis Tumour Core I/Actin %a Normal Core I/Actin %a Level of Expression * MIB-1b %
1 64/F HFC 46.2 ± 0.3 21.0 ± 0.5 2.2 1.1
2 33/M HFC 52.1 ± 1.8 22.8 ± 1.3 2.3 1.0
3 47/M HFC 52.1 ± 2.2 24.8 ± 1.1 2.1 0.9
4 59/F HFC 54.6 ± 0.8 22.2 ± 1.0 2.5 0.5
5 55/F HFC 47.7 ± 1.2 22.7 ± 0.8 2.1 0.9
6 24/F HFC 50.2 ± 0.9 23.9 ± 1.2 2.1 0.9
7 55/F HFC 41.5 ± 1.2 21.9 ± 1.4 1.9 0.8
8 64/F FC 46.4 ± 2.8 25.8 ± 1.6 1.8 1.1
9 46/F FC 48.9 ± 2.1 23.4 ± 0.8 2.1 1.6
10 71/F HmFA 47.2 ± 2.7 22.6 ± 1.8 2.1 1.1
11 24/F mFA 47.3 ± 3.3 26.4 ± 0.8 1.8 0.3
12 69/F mFA 45.1 ± 2.3 27.6 ± 1.3 1.6 0.0
13 57/F mFA 42.8 ± 1.8 22.5 ± 0.9 1.9 0.5
14 27/F mFA 48.8 ± 2.2 23.2 ± 1.1 2.1 0.9
15 53/F mFA 49.0 ± 2.1 22.7 ± 0.8 2.2 1.1
16 65/F mFA 52.4 ± 2.4 24.9 ± 0.9 2.1 0.7
17 31/F mMFA 35.8 ± 2.3 27.6 ± 1.3 1.3 0.1
18 52/F PC 30.0 ± 0.2 27.3 ± 0.1 1.1 0.7
19 46/F PC 24.2 ± 0.5 26.9 ± 0.1 0.9 1.1
20 52/F PC 39.8 ± 2.6 37.3 ± 0.0 1.1 0.7
21 47/F PC 26.7 ± 3.4 33.5 ± 3.7 0.8 3.0
22 52/F PC 16.7 ± 0.6 24.6 ± 0.4 0.7 0.7
23 68/F PC 24.1 ± 0.8 24.0 ± 0.6 1.0 0.8
24 60/F HPC 20.9 ± 1.2 23.2 ± 0.9 0.9 1.5
25 62/F HPC 16.4 ± 1.2 22.2 ± 0.8 0.7 0.4
26 11/M HPC 27.4 ± 0.9 22.8 ± 2.1 1.2 1.1
27 30/F HMFA 19.9 ± 0.1 28.6 ± 2.3 0.7 0.4
28 42/F MFA 18.5 ± 0.1 24.8 ± 0.1 0.7 0.6
29 52/F MFA 22.7 ± 2.3 25.4 ± 0.3 0.9 1.0
30 62/F MFA 22.3 ± 0.2 23.0 ± 0.1 1.0 0.2
31 54/F MFA 20.9 ± 0.7 25.8 ± 0.8 0.8 0.9
  1. F – Female; M – Male; HFC – Follicular carcinoma composed of Hürthle cells; FC – Follicular carcinoma; PC – Papillary carcinoma; HPC – Papillary carcinoma composed of Hürthle cells; mFA – Microfollicular adenoma; MFA – Macrofollicular adenoma; mMFA – Micro/macrofollicular adenoma; HmFA – Microfollicular adenoma composed of Hürthle cells; HMFA – Macrofollicular adenoma composed of Hürthle cells; Core I/Actin – Ratio between the expression of Core I gene and β-actin gene. *Values are expressed as ratio between the mean values obtained in tumours and normal tissues (previous columns). aResults are expressed as mean ± s.d. of three experiments. bOnly tumoural MIB-1 indexes are shown.