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Table 3 Univariate survival analysis of 20 CRC patients with liver metastases stratified by TS mRNA level and clinical response.

From: Thymidylate synthetase mRNA levels are increased in liver metastases of colorectal cancer patients resistant to fluoropyrimidine-based chemotherapy

  Univariate analysis*
  N (%) HR 95% CI
Response    
CR + PR 6 (30) 1  
SD + PD 14 (70) 3.31 (1.06–10.32)
Chi-square; p value χ2 = 4.24; p = 0.04
TS mRNA level    
<13 10 (50) 1  
>13 10 (50) 1.34 (0.52–3.44)
Chi-square; p value χ2 = 0.48; p = 0.54
  1. *Cox proportional hazard ratio (HR) and corresponding 95% confidence interval (CI). Reference value.