TY - JOUR AU - Hidalgo, Alfredo AU - Monroy, Alberto AU - Arana, Rosa Ma AU - Taja, Lucía AU - Vázquez, Guelaguetza AU - Salcedo, Mauricio PY - 2003 DA - 2003/03/20 TI - Chromosomal imbalances in four new uterine cervix carcinoma derived cell lines JO - BMC Cancer SP - 8 VL - 3 IS - 1 AB - Uterine cervix carcinoma is the second most common female malignancy worldwide and a major health problem in Mexico, representing the primary cause of death among the Mexican female population. High risk human papillomavirus (HPV) infection is considered to be the most important risk factor for the development of this tumor and cervical carcinoma derived cell lines are very useful models for the study of viral carcinogenesis. Comparative Genomic Hybridization (CGH) experiments have detected a specific pattern of chromosomal imbalances during cervical cancer progression, indicating chromosomal regions that might contain genes that are important for cervical transformation. SN - 1471-2407 UR - https://doi.org/10.1186/1471-2407-3-8 DO - 10.1186/1471-2407-3-8 ID - Hidalgo2003 ER -