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Table 3 Mann-Whitney U Test comparisons of expression fold changes from SU5416 treatment and control arms (Trial A).

From: Expression profiling of blood samples from an SU5416 Phase III metastatic colorectal cancer clinical trial: a novel strategy for biomarker identification

  P-value of Mann-Whitney U Test
Gene Affymetrix SYBR Green RT-PCR
  (n = 23) (n = 31)
MMP-9 0.0025 0.0748
Thrombospondin 1 0.0267 0.7186
CD24 0.0006 0.0057
Defensin α 3 0.0002 0.2196
Lactoferrin 0.0002 0.0065
Lipocalin 2 0.0005 0.0057
  1. Separate comparisons were performed on expression change values (predose day 56: predose day 1 ratios) from Affymetrix analysis and from SYBR Green RT-PCR validation experiments. P-values ≤ 0.05 were considered significant.