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Table 3 Pancreas

From: Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis

Author

Cases n

Cotrolsa/Cohortb

Source population

Exposure definition

Exposure assessment

Drug

RR

95% CI

Coogan et al. [26]

491

5,833a

Hospital based

>4 days/week for >3 months. Continuing use during 1 year of lag time

Personal Interview

NSAIDs (7%)

0.8

0.5–1.1

Langman et al. [36]

513

1,535a

Population based

>7 prescriptions during months 13–36 before index date

Automated Database

NSAIDs (7%)

1.49

1.02–2.18

Menezes et al. [49]

194

582a

Hospital based

>1 tablet/week for at least 6 months

In-hospital Questionnaire

Aspirin (44%)

1.00

0.72–1.39

Schreinemachers et al. [43]

30

12,668b

Cohort

Ever use of aspirin in the 30 days prior to start date

Mailed Questionnaire

Aspirin (59%)

0.67

0.33–1.36

Anderson et al. [23]

80

28,283b

Cohort

>6 times/week at baseline

Mailed Questionnaire

Aspirin (21%)

0.40

0.20–0.82

      

NA-NSAIDs (NR)

1.28

0.68–2.43

  1. Prevalence of exposure among controls/cohort