Skip to main content

Table 2 Stomach

From: Effects of non-steroidal anti-inflammatory drugs on cancer sites other than the colon and rectum: a meta-analysis

Author Cases n Controlsa/Cohortb Source population Exposure definition Exposure assessment Drug RR 95% CI
Farrow et al. [30] 612 687a Population based >1 tablet/week during >6 months. 1 year lag time Personal Interview Aspirin (31%) 0.76 0.60–0.97
  610      NA-NSAIDs (13%) 0.79 0.56–1.10
Akre et al. [22] 480 1,055a Population based >30 tablets/month. 2 years lag time Personal Interview Aspirin (3%) 0.8 0.7–1.1
       NA-NSAIDs 1.1 0.6–1.4
Zaridze et al. [48] 448 610a Hospital based >2 days/week for >6 months In-hospital Questionnaire Aspirin (14%) 0.60 0.41–0.90
       NSAIDs (17%) 0.65 0.45–0.93
Langman et al. [36] 613 1,837a Population based >7 prescriptions during months 13–36 before index date Automated Database NSAIDs (8%) 0.51 0.33–0.79
Coogan et al. [26] 250 5,883a Hospital based >4 days/week for >3 months. Continuing use during 1 year of lag time Personal Interview NSAIDs (7%) 0.3 0.1–0.6
Thun et al. [46] 266 635,031b Cohort More than 16 times per month for at least one year Mailed Questionnaire Aspirin (11%) 0.53 0.34–0.81
Schreinemachers et al. [43] 39 12,668b Cohort Ever use of aspirin in the 30 days prior to start date Personal Interview Aspirin (59%) 0.93 0.49–1.74
  1. Prevalence of exposure among controls/cohort; Exposure definition not provided.