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Figure 3 | BMC Cancer

Figure 3

From: Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line

Figure 3

Effect of putrescine supplementation on cell growth inhibition by I3C and DFMO. Cells were treated with I3C (SW480 175 μM; HT29 250 μM; HCEC 180 μM) or DFMO (SW480 50 μM; HT29 and HCEC 125 μM) or DMSO (control) and cultured in the presence or absence of putrescine (5–500 μM) for 7 days and then counted as described in Materials and Methods. Results are mean ± SD (n = 4), a indicates bars which are significantly different from control (DMSO without putrescine) group, b indicates significant difference from the I3C alone treatment, and c indicates significant difference from the DFMO alone treatment (P < 0.05).

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