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Table 2 Diagnostic characters identified in the main nodes of the MCF-7 phylogenetic tree. Characters specific of each node (whose occurrence has been associated with the emergence of the corresponding branch) are presented in bold type sets. Events in italics correspond to characters passed on from ancestors.

From: Genetic variability in MCF-7 sublines: evidence of rapid genomic and RNA expression profile modifications

MCF-7-ATCC MCF-7-R MCF-7-MG MCF-7-MVLN
Loss 1p32-p36 Loss 1p31-p36 Loss 1p31-p36 Loss 1p31-p36
  Gain 1p13 Gain 1p13 Gain 1p13
  Gain 1q31 Gain 1q31 Gain 1q31
  Loss 11q42-q44 Loss 11q42-q44 Loss 11q42-q44
Loss 2q36-q37 Loss 2q36-q37 Loss 2q36-q37 Loss 2q36-q37
  Gain 3q26 Gain 3q26 Gain 3q26
    Loss 5q33
   Loss 6q25-q27 Loss 6q25-q27
  Gain 7q22 Gain 7q22 Gain 7q22
Loss 8p11-p23 Loss 8p11-p23 Loss 8p11-p23 Loss 8p11-p23
Gain 8q22-q23 Gain 8q22-q23 Gain 8q22-q23 Gain 8q22-q23
  Loss 11q23-q25 Loss 11q23-q25 Loss 11q23-q25
  Loss 12p13 Loss 12p13 Loss 12p13
  Gain 12q15-q21 Gain 12q15-q21 Gain 12q15-q21
  Loss 13q31-q34 Loss 13q31-q34 Loss 13q31-q34
Gain 14q21-q23 Gain 14q21 -q24 Gain 14q21-q24 Gain 14q21-q24
    Gain 15q26
    Gain 16p11
  Loss 17p11-p13 Loss 17p11-p13 Loss 17p11-p13
Gain 17q22-q24 Gain 17q22-q24 Gain 17q22-q24 Gain 17q22-q24
Loss 18q12-q23 Loss 18q12-q23 Loss 18q12-q23 Loss 18q12-q23
Loss 19p13-q13 Loss 19p13-q13 Loss 19p13-q13 Loss 19p13-q13
   Loss 20p11-p13 Loss 20p11-p13
  Gain 20q12-q13 Gain 20q12-q13 Gain 20q12-q13
  Loss 21p13-q22 Loss 21p13-q22 Loss 21p13-q22