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Table 1

From: Chromosomal aberrations in benign and malignant Bilharzia-associated bladder lesions analyzed by comparative genomic hybridization

  

Histopathology

 

FISH

CGH imbalances

Lab No

Sex/Age

Type

Grade

Stage

Other

 

Losses

Gains

Benign

        

747–98

M/65

Ch. inflammation

      

738–98

F/53

Ch. inflammation

      

162–99

M/70

Ch. Inflammation Moderate dysplasia

      

548–98

M/51

Granuloma

  

CBO

   

352–99

F/55

Granuloma

  

CBO

Xc 3, AR 1

  

286–98

M/45

Granuloma with inflammatory polyp

   

9c 1, 17c 2

9p, 16p, 22q

 

Malignant

        

453–99

F/49

SCC

G1

?

CBO

topo 1

  

2228–99

F/60

SCC

G1

 

CBO

9c 1, 17c 3, Xc 3

1 cen-p31, 3p,9pter-q13

19p

229–99

M/70

SCC

G2

T3

KCs

Xc 2, 17c 2

  

210–99

M/70

SCC

G3

T3

KCs

   

471–99

M/60

SCC

G3

?

CBO+SM

Xc 2, 17c 3

  

217–98

F/51

SCC

G3

T3

CBO

 

9p

 

476–98

M/53

SCC

G3

T3

CBO

9c 2, 17c 3

1p21-p22, 2q13-q21, 8p, 13q, 18q

19p

479–98

M/47

SCC

G2–3

 

CBO

 

2q13-q21, 8p

19p

345–98

M/61

TCC

G1

?

CBO+SM

   

240–98

F/55

TCC

G2

?

 

Xc 1, 9c 2,17c 2

  

746–98

F/60

TCC

G2

  

Xc 2–3, 9c2–3, 17c 2–6(4)

  

4540–98

M/62

TCC

G2

?

    

5605–97

M/50

TCC

G3

T3

SM

Xc 2, AR 3–5

8p21-pter

 

5653–98

F/50

TCC

G3

T3

 

Xc 1–3, 9c 2, 17c 2

1 cen-p31

5p, 17q, 20q

  1. SCC, squamous cell carcinoma; TCC, transitional cell carcin oma; G1, well differentiated; G2, moderately differentiated; G3, poorly differ entiated; CBO, calcified bilharzial ova; I K:Cs, keratinzed cells; SM, squamous metapla