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Table 1 Methylation Status of RAR β2 5' region in cervical SCC and cervical cancer cell lines

From: Methylation and silencing of the retinoic acid receptor-β2 gene in cervical cancer

Case number or type of cells

RNA expression %*

Southern blot analysis

MSP assay

1

5

nd

M

2

19

M

Nd

3

48

M

M

4

22

M

M

5

26,5

M

M

6

18

M

M

7

**

M

M

8

19

nd

M

9-20

95-103

U

U

HeLa

**

M

M

SiHa

**

M

M

CaSki

**

nd

M

  1. * The expression levels of RAR β2 mRNA in carcinomas relative to morphologically normal tissues (%), determinations by Northern blot analysis; the RAR β2 mRNA levels have been normalized to GAPDH. ** Expression of RAR β2 mRNA was extremely low in tumor and morphologically normal tissue or cell lines. nd – not done