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Table 3 SIR values(95% CI) in relation to tumour type and different time intervals of follow up since diagnosis of gynecomastia. Also number of individuals and personyears for each interval are shown. The lead time between gynecomastia and tumour diagnosis was for esophageal cancer 8 years (6–10 years), skin cancer 6 years (3–25 years) and testicular carcinoma 10 years (3–18) years.

From: Male gynecomastia and risk for malignant tumours – a cohort study

Tumour type Time interval since diagnosis of gynecomastia
  0–2 years >2–10 years =10 years overall
all sites 0.15(0.00–0.85) 1.19(0.81–1.68) 1.07(0.75–1.49) 1.03 (0.80–1.30)
testicle 0.00(0.00–116.2) 6.60(0.17–36.76) 6.02(0.73–21.73) 5.82 (1.20–17.00)
esophagus ca 0.00(0.00–46.43) 2.57(0.07–14.35) 6.31(0.76–22.79) 3.82 (0.79–11.17)  
skin cancer (melanoma excl.) 0.00(0.00–12.33) 2.23(0.72–5.20) 5.30(2.29–10.43) 3.21(1.71–5.48)
number 443 426 337 445
personyears 870 3076 4428 8375