Table 7 Bone mineral density and breast cancer risk
From: Bone mineral density and the subsequent risk of cancer in the NHANES I follow-up cohort
Cohort; Size | BMD Measure | Cases | Significant Association Breast | Uterus Also Assessed? | Significant Association Uterus |
|---|---|---|---|---|---|
SOF 9704 | DEXA; Radius, Hip, Calcaneus | 97 | Yes; Positive | No | |
Framingham 1373 | RG Metacarpal | 91 | Yes* Positive | No | |
FIT 8203 | DEXA Femur | 102 | Yes; Positive | No | |
NHANES-1 6046 | RA Metacarpal | 100 | Yes: post meno pausal only | Yes; 29 cases | Yes; Positive |
Sweden 18,000 Hip Fractures | Hip Fracture prior to cancer diagnosis | 253 | Yes; Inverse@ | Yes; 55 cases | No |
Sweden 9673 Breast Cancers | Hip Fracture after breast cancer diagnosis | 387 Hip Fractures | No | Yes; 2111 cases | Yes; Inverse@ |
Sweden 677 Forearm Fractures | Forearm fracture | 11 cases Breast Cancer | Yes; Inverse@ | Yes; 5 cases | Yes; Inverse@ |
Rochester, MN Case/Control 235 Breast Cancers | Osteoporotic Fracture before & after cancer diagnosis | No | No | ||
US Multistate Tumor Registry; Case/Control 5559 Breast Cancers & 739 Uterine Cancers | Past Fracture before cancer diagnosis | 352 Fractures < or = 5 years prior to Breast Cancer Diagnosis | Yes; Inverse@ | Yes; 35 Fractures | Yes; Inverse@ |