Table 4 Bone mineral density and subsequent incidence of breast cancer
From: Bone mineral density and the subsequent risk of cancer in the NHANES I follow-up cohort
Number in Cohort | Number of Cases | Incidence Rate (cases/100 person years) | Age, Race & BMI Adjusted Rate Ratio (95% CI) | p-value for rate ratio | |
|---|---|---|---|---|---|
Breast Cancer (all Women) | |||||
All | 3108 | 100 | 1.94 | ||
RA BMD | |||||
<95 | 890 | 26 | 1.95 | 1 | |
95–105 | 635 | 35 | 3.26 | 2.19 (1.27–3.77) | P = 0.005 |
105–115 | 635 | 15 | 1.19 | 1.00 (0.49–2.020 | P = 0.99 |
>115 | 858 | 24 | 1.60 | 1.45 (0.75–2.82) | P = 0.27 |
Test for Linear Trend | P = 0.74 | ||||
Breast Cancer (Women over 55 Years Old) | |||||
All | 1091 | 43 | 2.68 | ||
RA BMD | |||||
<80.3 | 272 | 10 | 2.71 | 1 | |
80.3–89.7 | 273 | 2 | 0.49 | 0.19 (0.04–0.88) | P = 0.03 |
89.7–99.9 | 273 | 16 | 3.90 | 1.65 (0.73–3.75) | P = 0.23 |
>99.9 | 273 | 15 | 3.59 | 1.66 (0.69–3.99) | P = 0.26 |
Test for Linear Trend | P = 0.04 |