Figure 6
From: Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth
L44 tumour responses to a dose escalation of Ad Adapt mhATF-BPTI. The animals were treated with daily iv injections of the vector for 4 consecutive days. The treatment began 20 days after the tumour implantation when the tumours were 8 × 8 × 8 mm. Arrows indicate days of injection. The doses employed are 108iu (open triangles, n = 4), 109iu (open circles, n = 4), and 2.5 109iu (open squares, n = 6) Ad Adapt mhATF-BPTI and 1010iu (closed squares, n = 6) Ad Adapt empty. Vertical lines indicate SD.