Figure 11
From: Adenoviral gene transfer of angiostatic ATF-BPTI inhibits tumour growth
Influence of the tumour mass on the anti tumour effect of ATF-BPTI in the CC531model. The animals were treated when the tumours were about 100 mm3 (C) or about 1000 mm3 (D). The colon adenocarcinoma CC531 grows in Wag / Rij rats in which high plasma levels could not be obtain, therefore the animals were treated by one intratumoral injection of 1010 iu Ad Adapt mhAB or Ad Adapt empty. The p value between the treated group and the control is indicated in the figure when the difference was significant according to the ANOVA test. The number of animals per group is indicated in the figures. Vertical lines indicate SD.