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Table 2 Growth of infected U87 cells in nude mice.

From: Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo

 

U87

U87-WT

U87-MK

# cellsa

#tumors (%)

Weight (g)

#tumors (%)

Weight (g)

#tumors (%)

Weight (g)

5 × 105

4/14 (29%)

0.48 ± 0.11

11/16 (69%)

0.67 ± 0.15

2/14 (14%)

0.13* ± 0.02

106

16/24 (67%)

0.43 ± 0.13

16/18 (89%)

0.57 ± 0.1

11/24 (46%)

0.12* ± 0.02

  1. Weight is given as mean ± SEM. (a) mice with 5 × 105 cells sacrificed after 10 weeks, mice with 106 cells sacrificed after 6 weeks. Asterisks denote statistical significance (P < 0.05) versus parental cells
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BMC Cancer

ISSN: 1471-2407

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