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Table 1 Effect of antibody αIR3 on transformation and tumor growth.

From: Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo

 

Untreated

αIR3

Mouse IgG

Colonies in soft agar

28 ± 3

11 ± 2

27 ± 2

Tumors in nude mice

-

4/16 (25%)

11/16 (69%)