From: Retroviral expression of a kinase-defective IGF-I receptor suppresses growth and causes apoptosis of CHO and U87 cells in-vivo
Untreated
αIR3
Mouse IgG
Colonies in soft agar
28 ± 3
11 ± 2
27 ± 2
Tumors in nude mice
-
4/16 (25%)
11/16 (69%)