Figure 5

Principal component analysis (PCA) carried out to explore the difference between genes and relationships with clinicopathological parameters. The analysis of gene expression was made by PCA. On the dimension 1 (Dim 1), a clear discrimination can be noted between overexpressed genes (AR, SRC3 and EZH2) and under expressed genes (RAR beta 2, ER alpha, PGR and RGMA). The overexpression of AR, SRC3 and EZH2 gene correlated with PSA level (PSA), clinical stage (patho) and Gleason score (Gleason).