Figure 1From: INTRAGO: intraoperative radiotherapy in glioblastoma multiforme – a Phase I/II dose escalation study Study Workflow. Legend: KPS, Karnofsky Performance Status; GBM, glioblastoma multiforme; LENT-SOMA, Late Effects in Normal Tissues - Subjective, Objective, Management and Analytic (LENT-SOMA). IORT, intraoperative radiotherapy; EBRT, external beam radiotherapy; DLT, dose-limiting toxicity; MRI, magnetic resonance imaging.Back to article page