Skip to main content
Figure 2 | BMC Cancer

Figure 2

From: Endothelial cell-derived interleukin-6 regulates tumor growth

Figure 2

STAT3 phosphorylation induced by endothelial cell-secreted factors is independent of Akt and ERK phosphorylation. Western blot for phosphorylated and total STAT3, Akt, and ERK in HeLa serum-starved overnight and exposed to A, HDMEC conditioned medium (CM) or unconditioned medium (EBM) for the indicated time points. In addition, HeLa were pre-incubated for 1 to 2 hours with B, 20 μM Stattic; C, 20 μM LY294002; or D, 20 μM U0126, and then exposed to HDMEC CM or EBM in presence of the specific inhibitor for the indicated time points.

Back to article page