The analysis was routinely adjusted on histology and cancer spread. Sex and chemotherapy doublet were proposed to the model but not kept at the final step. The analysis was stratified on ECOG-PS and hospital.
*In the model with RECIST, −2log likelihood = 563.762 with 6 degrees of freedom. In the model with UCSTS changes, −2log likelihood = 568.585 with 5 degrees of freedom.