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Figure 4 | BMC Cancer

Figure 4

From: Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma

Figure 4

SIRT1 induces epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma (HCC) cells. (A) - (D) RT-PCR was used to detect changes in the expression of EMT-associated genes in HCC cells treated with nicotinamide (NAM) or resveratrol (RES). Results represent means of triplicate experiments ± standard errors (*P < 0.05). (E) Immunofluorescence staining for E-cadherin and vimentin was performed in HepG2 and SMMC-7721 cells that were either untreated or treated with NAM or RES. Nuclei were counterstained with DAPI (×200).

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