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Figure 2 | BMC Cancer

Figure 2

From: Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma

Figure 2

Overexpression of SIRT1 promotes hepatocellular carcinoma (HCC) cell migration and invasion. (A) SMMC-7721 cells were transfected with adenoviral vectors, siRNA sequences, or their corresponding mock sequences to knockdown or overexpress SIRT1 at the protein level. (B) and (C) SMMC-7721 and HepG2 cells were transduced with adeno-associated virus to express SIRT1 or siRNA to knockdown SIRT1. Migration of pretreated HCC cells was determined by wound healing assay (A, ×200) and the invasiveness of the pretreated HCC cells was determined by Transwell assay (B, ×200, *P < 0.05).

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